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KMID : 0363220070450121322
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Korean Journal of Dermatology
2007 Volume.45 No. 12 p.1322 ~ p.1324
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A Case of Argyria
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Kim Sun-Ji
Park Hyun-Jeong
Lee Jun-Young
Cho Baik-Kee
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Abstract
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Argyria is a rare skin discoloration caused by the deposition of silver granules in the skin. We report a case of argyria occurring in a 46-year-old woman due to ingestion of colloidal silver solution over 2 years. She had a diffuse, slate gray discoloration on her face and hands. The biopsy specimen from the face revealed melanin hyperpigmentation in the epidermal basal layer. Numerous, round, tiny brown-black granules were deposited in the basement membrane surrounding eccrine glands. Silver solution is being advertised as a cure for a variety of diseases and is commercially available as a ’food supplement’. This case report highlights the potential risk of adverse effects following the use of food supplements.
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KEYWORD
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Argyria, Food supplement, Silver solution
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